Powergesic MR Tablet

Powergesic MR Tablet

Jenburkt Pharmaceuticals Ltd
Uses of Powergesic MR Tablet:
Pain relief, Fever, Pain relief
Composition of Powergesic MR Tablet:
Chlorzoxazone 500mg + Paracetamol / Acetaminophen 325mg + Diclofenac 50mg
MRP: 199.25 Inclusive of all Taxes
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*Product images are for illustrative purposes only and may differ from the actual product.
Description
Pain due to muscle spasm

Uses

Chlorzoxazone is generally used in treatment for muscle relaxation. It relieves painful spasms of the skeletal muscles.
Paracetamol / Acetaminophen is generally used in treatment for pain relief and fever. It is used to relieve pain in conditions like headache, muscle pain, or dental pain.
Diclofenac is generally used in treatment for pain relief. It relieves pain in conditions like headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, or painful menses.

Side effects

  • Diarrhoea
  • Dizziness
  • Heartburn
  • Indigestion
  • Loss of appetite
  • Nausea
  • Sleepiness
  • Stomach pain / epigastric pain
  • Stomach ulcer
  • Stomach upset
  • Vomiting
  • Weakness

How to use

Consume this medicine in the dosage and duration as per your doctors advise. While taking Paracetamol / Acetaminophen, swallow it completely without crushing, breaking or chewing it. Paracetamol / Acetaminophen is to be taken with food.
Consume this medicine in the dosage and duration as per your doctors advise. While taking Diclofenac, swallow it completely without crushing, breaking or chewing it. Diclofenac is to be taken with food.

How it works

Chlorzoxazone is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles.
Paracetamol / Acetaminophen is an analgesic and anti-pyretic. It relieves the pain & reduces the fever by blocking the release of some chemical messengers that typically cause fever and pain.
Diclofenac is a belongs to the group of non-steroidal anti-inflammatory drugs (NSAID). It blocks the release of chemical messengers that cause inflamation & pain (redness & swelling) thereby making the condition better.
Q. Is Chlorzoxazone an opiate/ narcotic/ steroid/ controlled substance/ addictive?
No. Chlorzoxazone is mephenesin like centrally acting muscle relaxant that is used to relieve muscle stiffness and pain. It is not a steroid, narcotic, addictive or controlled substance

Q. Does Chlorzoxazone be used for recreational purposes?
No, Chlorzoxazone or any other drug should not be used for recreational purpose. Use only when prescribed by the doctor

Q. Does Chlorzoxazone have aspirin or codeine in it?
No. It does not contain aspirin or codeine

Q. Does Chlorzoxazone induce drowsiness/ weight gain?
It is not known to cause weight gain, but may cause drowsiness. If you experience any such side effects, consult your doctor

Q. Is Chlorzoxazone like Vicodin?
No. Vicodin, which contains acetaminophen and hydrocodone, is used to relieve general pain. Chlorzoxazone is a muscle relaxant and different drug altogether

Q. Is Chlorzoxazone the same as Soma?
No. Soma caontains carisoprodol, another mephenesin-like centrally acting muscle relaxant. However, it totally different from Chlorzoxazone

Q. Can I take Chlorzoxazone with tramadol, naproxen or ibuprofen?
No known interaction data is available for these drugs. However, it doesn't mean that the Chlorzoxazone can be taken with tramadol, naproxen or ibuprofen. Always consult your doctor regarding the drug usage

Q. Can I take Chlorzoxazone with hydrocodone/ citalopram/ acetaminophen?
No. It is advisable not to take Chlorzoxazone with hydrocodone/ citalopram/ acetaminophen since interactions have been reported for this combination.

Q. Can I take Paracetamol / Acetaminophen with vitamin B complex?
Yes, Paracetamol / Acetaminophen can be practiced with vitamin B-complex. They are used together in the treatment of acute and painful diseases affecting nerves like trigeminal neuralgias, post-operative pain, etc. Paracetamol / Acetaminophen serves to relieve pain and vitamin B-complex helps the deficiency that might be producing your signs.

Q. Is Paracetamol / Acetaminophen use associated with Helicobacter pylori infection?
Paracetamol / Acetaminophen use isn't related to Helicobacter pylori infection. Painkiller medicines can develop the acid secretion in the stomach, worsen the symptoms of this infection and the risk of stomach and the intestine ulcer. Though, this risk is least with Paracetamol / Acetaminophen as compared to other painkillers.

Q. Can I take Paracetamol / Acetaminophen with fexofenadine?
Yes, Paracetamol / Acetaminophen can be used safely with fexofenadine. No drug interactions or any adverse effects have been recorded. These are practiced together to treat the symptoms of a cough, cold, flu or a sore throat and other allergic or viral diseases. Fexofenadine serves to reduce sneezing, itchy throat, runny nose, or eyes and Paracetamol / Acetaminophen helps to relieve pain or fever.

Q. Can I take Paracetamol / Acetaminophen with warfarin?
It is safe to use Paracetamol / Acetaminophen occasionally with warfarin as other painkillers like ibuprofen and aspirin can increase the risk of bleeding. However, on a long-term use, Paracetamol / Acetaminophen can also increase the risk of bleeding. Consult your doctor before taking them together as you may need to be monitored regularly.

Q. Can I take Paracetamol / Acetaminophen with tamsulosin?
Paracetamol / Acetaminophen can be taken with Tamsulosin. No adverse side effects or other interactions have been seen when they are practiced together. Tamsulosin is an alpha adrenergic receptor blocker used to treat symptoms of benign prostatic hyperplasia.

Q. Can I take Paracetamol / Acetaminophen with cetirizine?
Paracetamol / Acetaminophen can be taken safely with cetirizine. No drug-drug interactions or any adverse effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore throat and other allergic or viral diseases. Cetirizine helps to relieve sneezing, runny nose, itchy throat or eyes and Paracetamol / Acetaminophen helps to reduce pain or fever.

Q. Can I take Paracetamol / Acetaminophen with ibuprofen?
Yes, Paracetamol / Acetaminophen can be practiced with ibuprofen. Both help to reduce pain and fever and ibuprofen also reduces inflammation and swelling. Still, both enhance the acid secretion in the stomach and can produce acid reflux, heartburn, stomach, and intestinal ulcers and gut bleeding on long-term use.

Q. Does Paracetamol / Acetaminophen cause weight loss?
Paracetamol / Acetaminophen isn't known to cause weight loss. It is a pretty harmless drug for short-term treatment and can create minor and occasional side effects like lowering blood pressure, and allergic effects.

Q. Can anyone be allergic to Paracetamol / Acetaminophen?
There have been reports of hypersensitivity and allergic effect with the usage of Paracetamol / Acetaminophen. Symptoms of an allergy involve inflammation of the face, mouth, and throat, shortness of breath, urticaria, red rash, and severe itching. Stop using Paracetamol / Acetaminophen if you have such symptoms and immediately consult your physician.

Q. How beneficial is to use Paracetamol / Acetaminophen with diclofenac?
Paracetamol / Acetaminophen and Diclofenac are used together in case of fever and pain. Paracetamol / Acetaminophen has an early onset of effect and it serves in decreasing the symptoms till diclofenac starts acting. But, both are painkillers and can harm the stomach lining on long-term practice leading to acid reflux, stomach ulcers, heartburn, and bleeding.

Q. Can I take Paracetamol / Acetaminophen for stomach pain?
Paracetamol / Acetaminophen should not be used for stomach pain. You must consult your physician for this. The stomach pain could be due to some underlying disease, which needs attention.

Q. Can I take Paracetamol / Acetaminophen with aceclofenac?
Paracetamol / Acetaminophen can be used with aceclofenac for fever and pain. Paracetamol / Acetaminophen has an early onset of action and it helps in relieving the symptoms till Aceclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.

Q. Does Paracetamol / Acetaminophen treat sore-throat, flu or cold?
Paracetamol / Acetaminophen doesn't treat sore-throat, flu or cold though it can help in reducing fever and body pains associated with these conditions.

Q. Can I take Paracetamol / Acetaminophen with codeine?
Paracetamol / Acetaminophen and codeine can be used together. No drug interactions or any adverse effects have been recorded when they are practiced together. They are generally given together for the relief of mild to moderate pain due to different reasons.

Q. Does Paracetamol / Acetaminophen help a cough?
Paracetamol / Acetaminophen doesn't help in the relief of cough but it can help in reducing associated fever and body aches.

Q. Does Paracetamol / Acetaminophen contain alcohol?
Paracetamol / Acetaminophen does not contain any alcohol.

Q. Can I take Paracetamol / Acetaminophen with amoxicillin?
Paracetamol / Acetaminophen and amoxicillin can be taken together. Amoxicillin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Does Paracetamol / Acetaminophen have side effects?
Paracetamol / Acetaminophen is quite safe for short term usage. It has side effects if practiced in more than the dose recommended and for a long-term. Immediately consult a physician if there is a loss of appetite, dark colored urine, nausea, stomach pain, clay-colored stools or jaundice as it could be due to an overdose of Paracetamol / Acetaminophen.

Q. Is Paracetamol / Acetaminophen safe to use?
Paracetamol / Acetaminophen is safe to use in the dose as recommended by the physician. Using more than prescribed doses can do serious harm.

Q. Is it safe to take Paracetamol / Acetaminophen with erythromycin?
Paracetamol / Acetaminophen and Erythromycin can be taken together. Erythromycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of associated fever. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Is Paracetamol / Acetaminophen an antibiotic?
Paracetamol / Acetaminophen isn't an antibiotic drug. It's an analgesic (pain-killer) and antipyretic (for the relief of fever), whereas an antibiotic is beneficial for the treatment of infections.

Q. Can I take Paracetamol / Acetaminophen with metronidazole?
Paracetamol / Acetaminophen and Metronidazole can be used together. No drug interactions or any adverse effects have been reported when used together.

Q. Can I take Paracetamol / Acetaminophen with homeopathic medicine?
consult your doctor before taking Paracetamol / Acetaminophen with homeopathic medicine as there is no information available on this.

Q. Is it safe to take Paracetamol / Acetaminophen with Tramadol?
Paracetamol / Acetaminophen can be taken with Tramadol. They are practiced together for medium to severe pain in several conditions and their use is correlated with general side effects like nausea, dizziness, and sleepiness. No drug interactions have been reported when they are practiced together.

Q. Can I take Paracetamol / Acetaminophen with Azithromycin?
Paracetamol / Acetaminophen and Azithromycin can be taken together. Azithromycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Is it safe to take Paracetamol / Acetaminophen with Naproxen?
Paracetamol / Acetaminophen can be taken with Naproxen. Both are painkillers and belong to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and are practiced to relieve pain and fever. Though, long-term usage affects the stomach lining and develop acid secretion which can lead to side effects like heartburn, acid reflux, stomach and intestinal ulcers and bleeding.

Q. Can a patient with high blood pressure take Paracetamol / Acetaminophen?
use of Paracetamol / Acetaminophen occasionaly is safe in patients with high blood pressure. Still, if it is to be taken for a long time, you must talk to your doctor. Paracetamol / Acetaminophen belongs to the group of painkillers called analgesics and antipyretics and these drugs can limit the action of medicines taken by the patient for control of high blood pressure.

Q. Does Paracetamol / Acetaminophen interact with vitamin C?
Vitamin C can be used with Paracetamol / Acetaminophen. However, vitamin C enhances the blood levels of other drugs similar to Paracetamol / Acetaminophen, so it is recommended to discuss to your physician if you have to take both these drugs for a long-term.

Q. What happens if you take an overdose of Paracetamol / Acetaminophen?
An overdose of Paracetamol / Acetaminophen can create potentially life-threatening liver damage, which is the most dangerous side effect. Initial signs may include nausea, vomiting, profuse sweating, and general tiredness. Kidney damage reduced platelet count furthermore coma may also happen. Quickly consult a physician or consult an emergency in the case of suspected overdosage.

Q. Can I take Paracetamol / Acetaminophen with hyoscine?
Yes, Paracetamol / Acetaminophen and hyoscine can be taken together. Hyoscine is used to relieve pain and cramps of the stomach, gut, urinary bladder and urinary tract while Paracetamol / Acetaminophen is used to relieve mild to moderate pain of a headache, toothache, muscle pain, joint pain, and fever. Together they can be advised by a doctor for painful conditions of the gut and urinary tract.

Q. Can I take Paracetamol / Acetaminophen with Betahistine?
Paracetamol / Acetaminophen can be used with Betahistine. There are no reported drug interactions or adverse effects when they are used together.

Q. Can I take Paracetamol / Acetaminophen with rabeprazole?
Paracetamol / Acetaminophen and Rabeprazole can be taken together. Rabeprazole is used to prevent Paracetamol / Acetaminophen (painkillers) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no clinically significant drug-drug interactions or harmful effects seen when they are used together.

Q. How beneficial is to take urofollitropin alpha with Paracetamol / Acetaminophen?
Urofollitropin alpha is given as a subcutaneous injection with the human chorionic gonadotropin (hCG) hormone to assist in ovulation and fertility. Urofollitropin alpha can cause abdominal or pelvic pain or pain and swelling at the injection site in some patients which can be relieved by taking Paracetamol / Acetaminophen.

Q. Can vitamin D be taken safely with Paracetamol / Acetaminophen?
Paracetamol / Acetaminophen and vitamin D can be taken together. Patients with osteoarthritis who are on vitamin D and calcium may need to take Paracetamol / Acetaminophen for the relief of any associated pain. No drug interactions or any adverse effects have been reported.

Q. Can I take clindamycin with Paracetamol / Acetaminophen?
Paracetamol / Acetaminophen and Clindamycin can be taken together. Clindamycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen may be given along, for the relief of associated fever. No drug-drug interactions have been reported clinically. However, both are known to cause liver damage. Talk to your doctor if you need them for a long time.

Q. Does Paracetamol / Acetaminophen affect the liver?
Usage of Paracetamol / Acetaminophen for a longer duration and more than advised doses can cause liver damage ranging from abnormal liver tests to liver failure. If you are taking Paracetamol / Acetaminophen from a long time and have nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice, inform your doctor as these could be signs of an underlying liver damage.

Q. Can I take Paracetamol / Acetaminophen if I have hepatitis?
Paracetamol / Acetaminophen is considered to be the safest painkiller for people with hepatitis for mild to moderate pain and fever. Paracetamol / Acetaminophen is metabolized in the liver. so, consult your physician before taking Paracetamol / Acetaminophen if you have hepatitis as it can cause liver damage if taken in higher doses or for longer duration.

Q. What are the serious side effects of taking excess Paracetamol / Acetaminophen?
Potentially critical life-threatening liver damage is a serious side effect observed with an overdose of Paracetamol / Acetaminophen. Overdose can also create kidney injury, coma, and reduced platelet count. Initial signs of an overdose include nausea, vomiting, and general tiredness. Immediately consult a physician or reach an emergency in case of suspected overdose.

Q. Can Diclofenac be used along with warfarin?
No. Using Diclofenac together with warfarin can increase the risk of serious bleeding from the stomach (Higher than users of either drug alone). Inform your doctor before starting these medications.

Q. Is Diclofenac a painkiller?
Yes. Diclofenac is a pain killer. In fact, it belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.

Q. Is Diclofenac a narcotic?
No, Diclofenac is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

Q. Can I use Diclofenac along with vitamins?
Yes, Diclofenac can be taken with vitamins. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Can Diclofenac be used for the treatment of hepatitis?
No, Diclofenac is not approved for the treatment of hepatitis. Hepatitis is a condition where the liver is inflamed. Diclofenac can, in fact, cause harm to the liver as a side effect.

Q. Can Diclofenac be used after C-section?
Yes, Diclofenac is a pain killer. C-section is the short name for Cesarean Section which is an operative procedure to deliver the baby through the mother's abdomen and uterus. Diclofenac can be used to treat the pain that may occur after the operation.

Q. Can I take Diclofenac along with misoprostol?
Yes. It can be taken together. Misoprostol protects the stomach from irritating gastric effects of Diclofenac. The combination of medication is used to treat arthritis in patients at high risk of getting stomach/intestinal ulcers and complications from the ulcers (such as bleeding).

Q. Can I take Diclofenac while I am on thyroxine?
Yes, Diclofenac can be taken with thyroxine. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Why Diclofenac should be stopped before surgery?
Since Diclofenac has been shown to have blood thinning effects, it can increase the risk of bleeding. Therefore, it is stopped before surgery to prevent excessive loss of blood.

Q. What are the contraindications for Diclofenac?
Diclofenac should not be used if there is an allergic reaction (hypersensitivity) to it, or other pain killers, active ulcer in the stomach, bleeding from the stomach, history of severe heart failure, liver failure, kidney failure and or heart attack.

Q. Can Diclofenac affect the chance of conceiving?
Yes. Diclofenac can sometime cause reversible infertility. Diclofenac by its mechanism of action, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Q. Why does Diclofenac cause an ulcer?
Diclofenac can cause damage to the lining cells of the stomach by several mechanisms, including the irritant effect on the cells, breaking of the protective barrier properties of lining cells, suppression of prostaglandin production of the stomach, reduction of stomach mucosal blood flow and interference with the repair of superficial injury of the stomach lining.

Q. Why is Diclofenac contraindicated in asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory drugs (NSAID) like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Q. Is Diclofenac good for back pain?
Yes, Diclofenac has been found to be effective to reduce back pain. Diclofenac is a pain killer that belongs to the NSAIDs (Non-Steroidal Anti-Inflammatory) class. Other NSAIDs have also been found to be useful in back pain eg. Ibuprofen and Naproxen.

Q. Can I use Diclofenac during my fever treatment?
Yes, Diclofenac can reduce fever. However, commonly used to reduce the pain, particularly that which is seen with Osteoarthritis, Rheumatoid Arthritis and Ankylosing spondylitis.

Q. Can I use Diclofenac to treat a sore throat?
Sore throat is mostly caused by bacteria so antibiotics are given to treat a sore throat whereas Diclofenac is a pain killer so it can be given in cases of throat pain associated with it but only under the prescription of a doctor.

Q. Can I use Diclofenac to treat urinary tract infections (UTI)?
Diclofenac can be used to treat the pain associated with urinary tract infection (UTI) but for complete treatment, a course of antibiotics will be required.

Q. Can Diclofenac cause sedation?
Diclofenac is not known to cause sedation. There have been rare, an isolated case report of sedation with the drug.

Q. Can I take Diclofenac for kidney stones?
Yes,Diclofenac can be used to relieve the pain due to kidney stones. However, there is also a risk of kidney damage with Diclofenac as its side effect. It is advised not to take Diclofenac for a prolonged time for this condition without adequate monitoring.

Q. Can I use Diclofenac for the treatment of arthritis?
Yes, Diclofenac is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis, and spondylitis.It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). .

Q. Can I use Diclofenac with diuretics?
No, Diclofenac should not be used with diuretics. Diclofenac reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Q. Can I use Diclofenac with mifepristone?
These drugs should not be used together as the effect of mifepristone may be lowered by Diclofenac. Mifepristone is used for medical abortion.

Q. Can I use Diclofenac with lithium?
No.These drugs should not be used together as Diclofenac increases the blood levels of lithium which may further increase the side effects.
  • Chlorzoxazone provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.Take it with or after food or a glass of milk.Chlorzoxazone may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.Avoid consuming alcohol when taking Chlorzoxazone as it may cause excessive drowsiness.Inform your doctor if you are pregnant, planning to conceive or breastfeeding.Don't stop taking it suddenly without talking to your doctor if you've been on it for a long time.
  • Good for pain relief and fever but not effective in joint pain due to poor anti-inflammatory action.Starts working within one hour. Wait for at least 4 hours before taking the next dose.Present in many over-the-counter (OTC) and prescription medicines. Avoid taking more than one paracetamol product at a time to prevent overdose. Doses >4 g/day (2 g in alcoholics) may cause liver, kidney or heart problems.Discontinue Paracetamol / Acetaminophen and inform your doctor immediately if rash occurs.For children, measure the doses of liquid Paracetamol / Acetaminophen using the measuring cup instead of a teaspoon to avoid under or over-dosage.Avoid excess alcohol intake (>3 glasses/day) when taking Paracetamol / Acetaminophen as it may cause liver damage.
  • You have been prescribed Diclofenac to relieve pain and inflammation.Take it with food or milk to prevent upset stomach.Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.Avoid consuming alcohol while taking Diclofenac as it can cause excessive drowsiness and increase your risk of stomach problems.Inform your doctor if you have a history of heart disease or stroke.Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

Product Details

SKU: PC-8144
Product Description: Powergesic MR Tablet is manufactured by Jenburkt Pharmaceuticals Ltd
Packing: Strip
Condition: New
Sold by: Pulse Pharmacy India Pvt. Ltd.
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