Doloforce Plus Tablet
Mankind Pharma Ltd
Uses of Doloforce Plus Tablet:
Pain relief, Pain relief, Fever
Composition of Doloforce Plus Tablet:
Piroxicam 20mg + Paracetamol / Acetaminophen 325mg
MRP:
₹
42.3
Inclusive of all Taxes
*Product images are for illustrative purposes only and may differ from the actual product.
Description
Pain relief
Uses
Piroxicam is generally used in treatment of pain relief. It relieves pain and inflammation in conditions like rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
Paracetamol / Acetaminophen is generally used in treatment for pain relief and fever. It is used to relieve pain in conditions like headache, muscle pain, or dental pain.
Paracetamol / Acetaminophen is generally used in treatment for pain relief and fever. It is used to relieve pain in conditions like headache, muscle pain, or dental pain.
Side effects
- Diarrhoea
- Indigestion
- Nausea
- Stomach pain
- Vomiting
How to use
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Consume this medicine in the dosage and duration as per your doctors advise. While taking Paracetamol / Acetaminophen, swallow it completely without crushing, breaking or chewing it. Paracetamol / Acetaminophen is to be taken with food.
Consume this medicine in the dosage and duration as per your doctors advise. While taking Paracetamol / Acetaminophen, swallow it completely without crushing, breaking or chewing it. Paracetamol / Acetaminophen is to be taken with food.
How it works
Piroxicam is a non-steroidal anti-inflammatory drug (NSAID). It makes the condition better by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
Paracetamol / Acetaminophen is an analgesic and anti-pyretic. It relieves the pain & reduces the fever by blocking the release of some chemical messengers that typically cause fever and pain.
Paracetamol / Acetaminophen is an analgesic and anti-pyretic. It relieves the pain & reduces the fever by blocking the release of some chemical messengers that typically cause fever and pain.
Frequently Asked Questions
Q. What is the difference between Piroxicam and diclofenac?
Both Piroxicam and diclofenac are pain killers. However, Piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Piroxicam.
Q. What is the difference between Piroxicam and naproxen?
Both Piroxicam and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Piroxicam.
Q. What is the difference between Piroxicam and meloxicam?
Both Piroxicam and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Piroxicam.
Q. What is the difference between Piroxicam and ketoprofen?
Both Piroxicam and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Piroxicam. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Piroxicam and tramadol?
Piroxicam is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Piroxicam and nimesulide?
Both Piroxicam and nimesulide are pain killers. However, Piroxicam is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to Piroxicam. It should not be used in children below 12 years of age.
Q. Can Piroxicam be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like Piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Piroxicam or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Piroxicam.
Q. Are Piroxicam and aspirin same?
No. Piroxicam and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Piroxicam be used along with dexamethasone?
No. Piroxicam should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Piroxicam be used with methocarbamol?
Yes. Methocarbamol can be used with Piroxicam as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Piroxicam be used along with paracetamol?
Yes. Paracetamol can be used with Piroxicam as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Piroxicam a NSAID?
Yes. Piroxicam is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Piroxicam a sulfa drug?
Piroxicam is a sulphur containing compound. Piroxicam can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Piroxicam a blood thinner?
No. Piroxicam is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Piroxicam a muscle relaxant?
No. Piroxicam is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Piroxicam a narcotic?
No. Piroxicam is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Piroxicam be used in hypertension?
No. Piroxicam is not a medication to control hypertension. It is important to note that Piroxicam decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Piroxicam.
Q. Can Piroxicam be used along with Losartan?
No. Piroxicam should not be combined with Losartan. It is important to note that Piroxicam decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piroxicam.
Q. Can Piroxicam be used with Lisinopril?
No. Piroxicam should be avoided with lisinopril. It is important to note that Piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piroxicam.
Q. Can Piroxicam be used with calcium channel blocker?
Yes. Piroxicam can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Piroxicam be used with Tizanidine?
Yes, Piroxicam can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Piroxicam?
Yes. Piroxicam can be combined with beta-cyclodextrin. Research has shown that combining Piroxicam with beta-cyclodextrin leads to faster onset of action of Piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Piroxicam?
Yes. There are alternatives to Piroxicam. Pain killers are prescribed according to the disease condition. Consult your doctor before starting Piroxicam or changing it to other medication.
Q. What are the contraindications for Piroxicam?
Contraindications to Piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Piroxicam be used in the treatment of allergy?
No. Piroxicam is not a drug to treat allergy. It is a pain killer.
Q. How long does Piroxicam work?
Piroxicam is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of Piroxicam increases when given for few weeks.
Q. Can you get high by using Piroxicam?
No. Piroxicam is not known to cause high. It is a non-narcotic painkiller.
Q. Can Piroxicam be used to treat menstrual cramp?
Piroxicam is not approved for the treatment of menstrual cramps. Research studies have shown that Piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Piroxicam for a migraine?
Piroxicam is not approved for the treatment of migraine. Research studies have shown that Piroxicam is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Piroxicam effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Piroxicam as the cause of back pain can be different for different person.
Q. Is Piroxicam affective in gout management?
Yes. Piroxicam can be given for the treatment of acute gout. Research studies have shown Piroxicam to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Piroxicam?
Yes. You can donate blood when on Piroxicam. Do inform your doctor before donating blood.
Q. Can I use Piroxicam if I am a diabetic?
Piroxicam in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Piroxicam so taking Piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Piroxicam if I have a deranged renal function?
No. Piroxicam should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Piroxicam lead to skin reactions?
Yes. Piroxicam is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Piroxicam if I am pregnant?
No. Piroxicam should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Piroxicam if I have peptic ulcer disease?
No. Piroxicam is contraindicated in cases of active peptic ulcer disease. Piroxicam is known to cause gastric ulceration and bleeding.
Q. Can I use Piroxicam if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Piroxicam lead to difficulty in conception?
Yes. Piroxicam can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Piroxicam be used with diuretics?
No. Piroxicam should not be used with diuretics. Piroxicam reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Piroxicam be used with lithium?
No. Piroxicam should not be used with lithium. Piroxicam leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Piroxicam be used with warfarin?
No. Piroxicam should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Piroxicam?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Piroxicam?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Piroxicam?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Q. Can I take Paracetamol / Acetaminophen with vitamin B complex?
Yes, Paracetamol / Acetaminophen can be practiced with vitamin B-complex. They are used together in the treatment of acute and painful diseases affecting nerves like trigeminal neuralgias, post-operative pain, etc. Paracetamol / Acetaminophen serves to relieve pain and vitamin B-complex helps the deficiency that might be producing your signs.
Q. Is Paracetamol / Acetaminophen use associated with Helicobacter pylori infection?
Paracetamol / Acetaminophen use isn't related to Helicobacter pylori infection. Painkiller medicines can develop the acid secretion in the stomach, worsen the symptoms of this infection and the risk of stomach and the intestine ulcer. Though, this risk is least with Paracetamol / Acetaminophen as compared to other painkillers.
Q. Can I take Paracetamol / Acetaminophen with fexofenadine?
Yes, Paracetamol / Acetaminophen can be used safely with fexofenadine. No drug interactions or any adverse effects have been recorded. These are practiced together to treat the symptoms of a cough, cold, flu or a sore throat and other allergic or viral diseases. Fexofenadine serves to reduce sneezing, itchy throat, runny nose, or eyes and Paracetamol / Acetaminophen helps to relieve pain or fever.
Q. Can I take Paracetamol / Acetaminophen with warfarin?
It is safe to use Paracetamol / Acetaminophen occasionally with warfarin as other painkillers like ibuprofen and aspirin can increase the risk of bleeding. However, on a long-term use, Paracetamol / Acetaminophen can also increase the risk of bleeding. Consult your doctor before taking them together as you may need to be monitored regularly.
Q. Can I take Paracetamol / Acetaminophen with tamsulosin?
Paracetamol / Acetaminophen can be taken with Tamsulosin. No adverse side effects or other interactions have been seen when they are practiced together. Tamsulosin is an alpha adrenergic receptor blocker used to treat symptoms of benign prostatic hyperplasia.
Q. Can I take Paracetamol / Acetaminophen with cetirizine?
Paracetamol / Acetaminophen can be taken safely with cetirizine. No drug-drug interactions or any adverse effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore throat and other allergic or viral diseases. Cetirizine helps to relieve sneezing, runny nose, itchy throat or eyes and Paracetamol / Acetaminophen helps to reduce pain or fever.
Q. Can I take Paracetamol / Acetaminophen with ibuprofen?
Yes, Paracetamol / Acetaminophen can be practiced with ibuprofen. Both help to reduce pain and fever and ibuprofen also reduces inflammation and swelling. Still, both enhance the acid secretion in the stomach and can produce acid reflux, heartburn, stomach, and intestinal ulcers and gut bleeding on long-term use.
Q. Does Paracetamol / Acetaminophen cause weight loss?
Paracetamol / Acetaminophen isn't known to cause weight loss. It is a pretty harmless drug for short-term treatment and can create minor and occasional side effects like lowering blood pressure, and allergic effects.
Q. Can anyone be allergic to Paracetamol / Acetaminophen?
There have been reports of hypersensitivity and allergic effect with the usage of Paracetamol / Acetaminophen. Symptoms of an allergy involve inflammation of the face, mouth, and throat, shortness of breath, urticaria, red rash, and severe itching. Stop using Paracetamol / Acetaminophen if you have such symptoms and immediately consult your physician.
Q. How beneficial is to use Paracetamol / Acetaminophen with diclofenac?
Paracetamol / Acetaminophen and Diclofenac are used together in case of fever and pain. Paracetamol / Acetaminophen has an early onset of effect and it serves in decreasing the symptoms till diclofenac starts acting. But, both are painkillers and can harm the stomach lining on long-term practice leading to acid reflux, stomach ulcers, heartburn, and bleeding.
Q. Can I take Paracetamol / Acetaminophen for stomach pain?
Paracetamol / Acetaminophen should not be used for stomach pain. You must consult your physician for this. The stomach pain could be due to some underlying disease, which needs attention.
Q. Can I take Paracetamol / Acetaminophen with aceclofenac?
Paracetamol / Acetaminophen can be used with aceclofenac for fever and pain. Paracetamol / Acetaminophen has an early onset of action and it helps in relieving the symptoms till Aceclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.
Q. Does Paracetamol / Acetaminophen treat sore-throat, flu or cold?
Paracetamol / Acetaminophen doesn't treat sore-throat, flu or cold though it can help in reducing fever and body pains associated with these conditions.
Q. Can I take Paracetamol / Acetaminophen with codeine?
Paracetamol / Acetaminophen and codeine can be used together. No drug interactions or any adverse effects have been recorded when they are practiced together. They are generally given together for the relief of mild to moderate pain due to different reasons.
Q. Does Paracetamol / Acetaminophen help a cough?
Paracetamol / Acetaminophen doesn't help in the relief of cough but it can help in reducing associated fever and body aches.
Q. Does Paracetamol / Acetaminophen contain alcohol?
Paracetamol / Acetaminophen does not contain any alcohol.
Q. Can I take Paracetamol / Acetaminophen with amoxicillin?
Paracetamol / Acetaminophen and amoxicillin can be taken together. Amoxicillin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Does Paracetamol / Acetaminophen have side effects?
Paracetamol / Acetaminophen is quite safe for short term usage. It has side effects if practiced in more than the dose recommended and for a long-term. Immediately consult a physician if there is a loss of appetite, dark colored urine, nausea, stomach pain, clay-colored stools or jaundice as it could be due to an overdose of Paracetamol / Acetaminophen.
Q. Is Paracetamol / Acetaminophen safe to use?
Paracetamol / Acetaminophen is safe to use in the dose as recommended by the physician. Using more than prescribed doses can do serious harm.
Q. Is it safe to take Paracetamol / Acetaminophen with erythromycin?
Paracetamol / Acetaminophen and Erythromycin can be taken together. Erythromycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of associated fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is Paracetamol / Acetaminophen an antibiotic?
Paracetamol / Acetaminophen isn't an antibiotic drug. It's an analgesic (pain-killer) and antipyretic (for the relief of fever), whereas an antibiotic is beneficial for the treatment of infections.
Q. Can I take Paracetamol / Acetaminophen with metronidazole?
Paracetamol / Acetaminophen and Metronidazole can be used together. No drug interactions or any adverse effects have been reported when used together.
Q. Can I take Paracetamol / Acetaminophen with homeopathic medicine?
consult your doctor before taking Paracetamol / Acetaminophen with homeopathic medicine as there is no information available on this.
Q. Is it safe to take Paracetamol / Acetaminophen with Tramadol?
Paracetamol / Acetaminophen can be taken with Tramadol. They are practiced together for medium to severe pain in several conditions and their use is correlated with general side effects like nausea, dizziness, and sleepiness. No drug interactions have been reported when they are practiced together.
Q. Can I take Paracetamol / Acetaminophen with Azithromycin?
Paracetamol / Acetaminophen and Azithromycin can be taken together. Azithromycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is it safe to take Paracetamol / Acetaminophen with Naproxen?
Paracetamol / Acetaminophen can be taken with Naproxen. Both are painkillers and belong to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and are practiced to relieve pain and fever. Though, long-term usage affects the stomach lining and develop acid secretion which can lead to side effects like heartburn, acid reflux, stomach and intestinal ulcers and bleeding.
Q. Can a patient with high blood pressure take Paracetamol / Acetaminophen?
use of Paracetamol / Acetaminophen occasionaly is safe in patients with high blood pressure. Still, if it is to be taken for a long time, you must talk to your doctor. Paracetamol / Acetaminophen belongs to the group of painkillers called analgesics and antipyretics and these drugs can limit the action of medicines taken by the patient for control of high blood pressure.
Q. Does Paracetamol / Acetaminophen interact with vitamin C?
Vitamin C can be used with Paracetamol / Acetaminophen. However, vitamin C enhances the blood levels of other drugs similar to Paracetamol / Acetaminophen, so it is recommended to discuss to your physician if you have to take both these drugs for a long-term.
Q. What happens if you take an overdose of Paracetamol / Acetaminophen?
An overdose of Paracetamol / Acetaminophen can create potentially life-threatening liver damage, which is the most dangerous side effect. Initial signs may include nausea, vomiting, profuse sweating, and general tiredness. Kidney damage reduced platelet count furthermore coma may also happen. Quickly consult a physician or consult an emergency in the case of suspected overdosage.
Q. Can I take Paracetamol / Acetaminophen with hyoscine?
Yes, Paracetamol / Acetaminophen and hyoscine can be taken together. Hyoscine is used to relieve pain and cramps of the stomach, gut, urinary bladder and urinary tract while Paracetamol / Acetaminophen is used to relieve mild to moderate pain of a headache, toothache, muscle pain, joint pain, and fever. Together they can be advised by a doctor for painful conditions of the gut and urinary tract.
Q. Can I take Paracetamol / Acetaminophen with Betahistine?
Paracetamol / Acetaminophen can be used with Betahistine. There are no reported drug interactions or adverse effects when they are used together.
Q. Can I take Paracetamol / Acetaminophen with rabeprazole?
Paracetamol / Acetaminophen and Rabeprazole can be taken together. Rabeprazole is used to prevent Paracetamol / Acetaminophen (painkillers) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no clinically significant drug-drug interactions or harmful effects seen when they are used together.
Q. How beneficial is to take urofollitropin alpha with Paracetamol / Acetaminophen?
Urofollitropin alpha is given as a subcutaneous injection with the human chorionic gonadotropin (hCG) hormone to assist in ovulation and fertility. Urofollitropin alpha can cause abdominal or pelvic pain or pain and swelling at the injection site in some patients which can be relieved by taking Paracetamol / Acetaminophen.
Q. Can vitamin D be taken safely with Paracetamol / Acetaminophen?
Paracetamol / Acetaminophen and vitamin D can be taken together. Patients with osteoarthritis who are on vitamin D and calcium may need to take Paracetamol / Acetaminophen for the relief of any associated pain. No drug interactions or any adverse effects have been reported.
Q. Can I take clindamycin with Paracetamol / Acetaminophen?
Paracetamol / Acetaminophen and Clindamycin can be taken together. Clindamycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen may be given along, for the relief of associated fever. No drug-drug interactions have been reported clinically. However, both are known to cause liver damage. Talk to your doctor if you need them for a long time.
Q. Does Paracetamol / Acetaminophen affect the liver?
Usage of Paracetamol / Acetaminophen for a longer duration and more than advised doses can cause liver damage ranging from abnormal liver tests to liver failure. If you are taking Paracetamol / Acetaminophen from a long time and have nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice, inform your doctor as these could be signs of an underlying liver damage.
Q. Can I take Paracetamol / Acetaminophen if I have hepatitis?
Paracetamol / Acetaminophen is considered to be the safest painkiller for people with hepatitis for mild to moderate pain and fever. Paracetamol / Acetaminophen is metabolized in the liver. so, consult your physician before taking Paracetamol / Acetaminophen if you have hepatitis as it can cause liver damage if taken in higher doses or for longer duration.
Q. What are the serious side effects of taking excess Paracetamol / Acetaminophen?
Potentially critical life-threatening liver damage is a serious side effect observed with an overdose of Paracetamol / Acetaminophen. Overdose can also create kidney injury, coma, and reduced platelet count. Initial signs of an overdose include nausea, vomiting, and general tiredness. Immediately consult a physician or reach an emergency in case of suspected overdose.
Both Piroxicam and diclofenac are pain killers. However, Piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Piroxicam.
Q. What is the difference between Piroxicam and naproxen?
Both Piroxicam and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Piroxicam.
Q. What is the difference between Piroxicam and meloxicam?
Both Piroxicam and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Piroxicam.
Q. What is the difference between Piroxicam and ketoprofen?
Both Piroxicam and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Piroxicam. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Piroxicam and tramadol?
Piroxicam is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Piroxicam and nimesulide?
Both Piroxicam and nimesulide are pain killers. However, Piroxicam is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to Piroxicam. It should not be used in children below 12 years of age.
Q. Can Piroxicam be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like Piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Piroxicam or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Piroxicam.
Q. Are Piroxicam and aspirin same?
No. Piroxicam and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Piroxicam be used along with dexamethasone?
No. Piroxicam should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Piroxicam be used with methocarbamol?
Yes. Methocarbamol can be used with Piroxicam as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Piroxicam be used along with paracetamol?
Yes. Paracetamol can be used with Piroxicam as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Piroxicam a NSAID?
Yes. Piroxicam is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Piroxicam a sulfa drug?
Piroxicam is a sulphur containing compound. Piroxicam can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Piroxicam a blood thinner?
No. Piroxicam is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Piroxicam a muscle relaxant?
No. Piroxicam is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Piroxicam a narcotic?
No. Piroxicam is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Piroxicam be used in hypertension?
No. Piroxicam is not a medication to control hypertension. It is important to note that Piroxicam decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Piroxicam.
Q. Can Piroxicam be used along with Losartan?
No. Piroxicam should not be combined with Losartan. It is important to note that Piroxicam decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piroxicam.
Q. Can Piroxicam be used with Lisinopril?
No. Piroxicam should be avoided with lisinopril. It is important to note that Piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Piroxicam.
Q. Can Piroxicam be used with calcium channel blocker?
Yes. Piroxicam can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Piroxicam be used with Tizanidine?
Yes, Piroxicam can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Piroxicam?
Yes. Piroxicam can be combined with beta-cyclodextrin. Research has shown that combining Piroxicam with beta-cyclodextrin leads to faster onset of action of Piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Piroxicam?
Yes. There are alternatives to Piroxicam. Pain killers are prescribed according to the disease condition. Consult your doctor before starting Piroxicam or changing it to other medication.
Q. What are the contraindications for Piroxicam?
Contraindications to Piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Piroxicam be used in the treatment of allergy?
No. Piroxicam is not a drug to treat allergy. It is a pain killer.
Q. How long does Piroxicam work?
Piroxicam is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of Piroxicam increases when given for few weeks.
Q. Can you get high by using Piroxicam?
No. Piroxicam is not known to cause high. It is a non-narcotic painkiller.
Q. Can Piroxicam be used to treat menstrual cramp?
Piroxicam is not approved for the treatment of menstrual cramps. Research studies have shown that Piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Piroxicam for a migraine?
Piroxicam is not approved for the treatment of migraine. Research studies have shown that Piroxicam is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Piroxicam effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Piroxicam as the cause of back pain can be different for different person.
Q. Is Piroxicam affective in gout management?
Yes. Piroxicam can be given for the treatment of acute gout. Research studies have shown Piroxicam to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Piroxicam?
Yes. You can donate blood when on Piroxicam. Do inform your doctor before donating blood.
Q. Can I use Piroxicam if I am a diabetic?
Piroxicam in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Piroxicam so taking Piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Piroxicam if I have a deranged renal function?
No. Piroxicam should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Piroxicam lead to skin reactions?
Yes. Piroxicam is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Piroxicam if I am pregnant?
No. Piroxicam should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Piroxicam if I have peptic ulcer disease?
No. Piroxicam is contraindicated in cases of active peptic ulcer disease. Piroxicam is known to cause gastric ulceration and bleeding.
Q. Can I use Piroxicam if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Piroxicam lead to difficulty in conception?
Yes. Piroxicam can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Piroxicam be used with diuretics?
No. Piroxicam should not be used with diuretics. Piroxicam reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Piroxicam be used with lithium?
No. Piroxicam should not be used with lithium. Piroxicam leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Piroxicam be used with warfarin?
No. Piroxicam should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Piroxicam?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Piroxicam?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Piroxicam?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
Q. Can I take Paracetamol / Acetaminophen with vitamin B complex?
Yes, Paracetamol / Acetaminophen can be practiced with vitamin B-complex. They are used together in the treatment of acute and painful diseases affecting nerves like trigeminal neuralgias, post-operative pain, etc. Paracetamol / Acetaminophen serves to relieve pain and vitamin B-complex helps the deficiency that might be producing your signs.
Q. Is Paracetamol / Acetaminophen use associated with Helicobacter pylori infection?
Paracetamol / Acetaminophen use isn't related to Helicobacter pylori infection. Painkiller medicines can develop the acid secretion in the stomach, worsen the symptoms of this infection and the risk of stomach and the intestine ulcer. Though, this risk is least with Paracetamol / Acetaminophen as compared to other painkillers.
Q. Can I take Paracetamol / Acetaminophen with fexofenadine?
Yes, Paracetamol / Acetaminophen can be used safely with fexofenadine. No drug interactions or any adverse effects have been recorded. These are practiced together to treat the symptoms of a cough, cold, flu or a sore throat and other allergic or viral diseases. Fexofenadine serves to reduce sneezing, itchy throat, runny nose, or eyes and Paracetamol / Acetaminophen helps to relieve pain or fever.
Q. Can I take Paracetamol / Acetaminophen with warfarin?
It is safe to use Paracetamol / Acetaminophen occasionally with warfarin as other painkillers like ibuprofen and aspirin can increase the risk of bleeding. However, on a long-term use, Paracetamol / Acetaminophen can also increase the risk of bleeding. Consult your doctor before taking them together as you may need to be monitored regularly.
Q. Can I take Paracetamol / Acetaminophen with tamsulosin?
Paracetamol / Acetaminophen can be taken with Tamsulosin. No adverse side effects or other interactions have been seen when they are practiced together. Tamsulosin is an alpha adrenergic receptor blocker used to treat symptoms of benign prostatic hyperplasia.
Q. Can I take Paracetamol / Acetaminophen with cetirizine?
Paracetamol / Acetaminophen can be taken safely with cetirizine. No drug-drug interactions or any adverse effects have been reported. These are used together to treat the symptoms of cold, cough, flu or a sore throat and other allergic or viral diseases. Cetirizine helps to relieve sneezing, runny nose, itchy throat or eyes and Paracetamol / Acetaminophen helps to reduce pain or fever.
Q. Can I take Paracetamol / Acetaminophen with ibuprofen?
Yes, Paracetamol / Acetaminophen can be practiced with ibuprofen. Both help to reduce pain and fever and ibuprofen also reduces inflammation and swelling. Still, both enhance the acid secretion in the stomach and can produce acid reflux, heartburn, stomach, and intestinal ulcers and gut bleeding on long-term use.
Q. Does Paracetamol / Acetaminophen cause weight loss?
Paracetamol / Acetaminophen isn't known to cause weight loss. It is a pretty harmless drug for short-term treatment and can create minor and occasional side effects like lowering blood pressure, and allergic effects.
Q. Can anyone be allergic to Paracetamol / Acetaminophen?
There have been reports of hypersensitivity and allergic effect with the usage of Paracetamol / Acetaminophen. Symptoms of an allergy involve inflammation of the face, mouth, and throat, shortness of breath, urticaria, red rash, and severe itching. Stop using Paracetamol / Acetaminophen if you have such symptoms and immediately consult your physician.
Q. How beneficial is to use Paracetamol / Acetaminophen with diclofenac?
Paracetamol / Acetaminophen and Diclofenac are used together in case of fever and pain. Paracetamol / Acetaminophen has an early onset of effect and it serves in decreasing the symptoms till diclofenac starts acting. But, both are painkillers and can harm the stomach lining on long-term practice leading to acid reflux, stomach ulcers, heartburn, and bleeding.
Q. Can I take Paracetamol / Acetaminophen for stomach pain?
Paracetamol / Acetaminophen should not be used for stomach pain. You must consult your physician for this. The stomach pain could be due to some underlying disease, which needs attention.
Q. Can I take Paracetamol / Acetaminophen with aceclofenac?
Paracetamol / Acetaminophen can be used with aceclofenac for fever and pain. Paracetamol / Acetaminophen has an early onset of action and it helps in relieving the symptoms till Aceclofenac starts working. However, both are pain killers and can affect stomach lining on long-term use leading to acid reflux, heartburn, and stomach ulcers and bleeding.
Q. Does Paracetamol / Acetaminophen treat sore-throat, flu or cold?
Paracetamol / Acetaminophen doesn't treat sore-throat, flu or cold though it can help in reducing fever and body pains associated with these conditions.
Q. Can I take Paracetamol / Acetaminophen with codeine?
Paracetamol / Acetaminophen and codeine can be used together. No drug interactions or any adverse effects have been recorded when they are practiced together. They are generally given together for the relief of mild to moderate pain due to different reasons.
Q. Does Paracetamol / Acetaminophen help a cough?
Paracetamol / Acetaminophen doesn't help in the relief of cough but it can help in reducing associated fever and body aches.
Q. Does Paracetamol / Acetaminophen contain alcohol?
Paracetamol / Acetaminophen does not contain any alcohol.
Q. Can I take Paracetamol / Acetaminophen with amoxicillin?
Paracetamol / Acetaminophen and amoxicillin can be taken together. Amoxicillin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Does Paracetamol / Acetaminophen have side effects?
Paracetamol / Acetaminophen is quite safe for short term usage. It has side effects if practiced in more than the dose recommended and for a long-term. Immediately consult a physician if there is a loss of appetite, dark colored urine, nausea, stomach pain, clay-colored stools or jaundice as it could be due to an overdose of Paracetamol / Acetaminophen.
Q. Is Paracetamol / Acetaminophen safe to use?
Paracetamol / Acetaminophen is safe to use in the dose as recommended by the physician. Using more than prescribed doses can do serious harm.
Q. Is it safe to take Paracetamol / Acetaminophen with erythromycin?
Paracetamol / Acetaminophen and Erythromycin can be taken together. Erythromycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of associated fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is Paracetamol / Acetaminophen an antibiotic?
Paracetamol / Acetaminophen isn't an antibiotic drug. It's an analgesic (pain-killer) and antipyretic (for the relief of fever), whereas an antibiotic is beneficial for the treatment of infections.
Q. Can I take Paracetamol / Acetaminophen with metronidazole?
Paracetamol / Acetaminophen and Metronidazole can be used together. No drug interactions or any adverse effects have been reported when used together.
Q. Can I take Paracetamol / Acetaminophen with homeopathic medicine?
consult your doctor before taking Paracetamol / Acetaminophen with homeopathic medicine as there is no information available on this.
Q. Is it safe to take Paracetamol / Acetaminophen with Tramadol?
Paracetamol / Acetaminophen can be taken with Tramadol. They are practiced together for medium to severe pain in several conditions and their use is correlated with general side effects like nausea, dizziness, and sleepiness. No drug interactions have been reported when they are practiced together.
Q. Can I take Paracetamol / Acetaminophen with Azithromycin?
Paracetamol / Acetaminophen and Azithromycin can be taken together. Azithromycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen is given along, for the relief of any associated pain and fever. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Is it safe to take Paracetamol / Acetaminophen with Naproxen?
Paracetamol / Acetaminophen can be taken with Naproxen. Both are painkillers and belong to the group of non-steroidal anti-inflammatory drugs (NSAIDs) and are practiced to relieve pain and fever. Though, long-term usage affects the stomach lining and develop acid secretion which can lead to side effects like heartburn, acid reflux, stomach and intestinal ulcers and bleeding.
Q. Can a patient with high blood pressure take Paracetamol / Acetaminophen?
use of Paracetamol / Acetaminophen occasionaly is safe in patients with high blood pressure. Still, if it is to be taken for a long time, you must talk to your doctor. Paracetamol / Acetaminophen belongs to the group of painkillers called analgesics and antipyretics and these drugs can limit the action of medicines taken by the patient for control of high blood pressure.
Q. Does Paracetamol / Acetaminophen interact with vitamin C?
Vitamin C can be used with Paracetamol / Acetaminophen. However, vitamin C enhances the blood levels of other drugs similar to Paracetamol / Acetaminophen, so it is recommended to discuss to your physician if you have to take both these drugs for a long-term.
Q. What happens if you take an overdose of Paracetamol / Acetaminophen?
An overdose of Paracetamol / Acetaminophen can create potentially life-threatening liver damage, which is the most dangerous side effect. Initial signs may include nausea, vomiting, profuse sweating, and general tiredness. Kidney damage reduced platelet count furthermore coma may also happen. Quickly consult a physician or consult an emergency in the case of suspected overdosage.
Q. Can I take Paracetamol / Acetaminophen with hyoscine?
Yes, Paracetamol / Acetaminophen and hyoscine can be taken together. Hyoscine is used to relieve pain and cramps of the stomach, gut, urinary bladder and urinary tract while Paracetamol / Acetaminophen is used to relieve mild to moderate pain of a headache, toothache, muscle pain, joint pain, and fever. Together they can be advised by a doctor for painful conditions of the gut and urinary tract.
Q. Can I take Paracetamol / Acetaminophen with Betahistine?
Paracetamol / Acetaminophen can be used with Betahistine. There are no reported drug interactions or adverse effects when they are used together.
Q. Can I take Paracetamol / Acetaminophen with rabeprazole?
Paracetamol / Acetaminophen and Rabeprazole can be taken together. Rabeprazole is used to prevent Paracetamol / Acetaminophen (painkillers) induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. There are no clinically significant drug-drug interactions or harmful effects seen when they are used together.
Q. How beneficial is to take urofollitropin alpha with Paracetamol / Acetaminophen?
Urofollitropin alpha is given as a subcutaneous injection with the human chorionic gonadotropin (hCG) hormone to assist in ovulation and fertility. Urofollitropin alpha can cause abdominal or pelvic pain or pain and swelling at the injection site in some patients which can be relieved by taking Paracetamol / Acetaminophen.
Q. Can vitamin D be taken safely with Paracetamol / Acetaminophen?
Paracetamol / Acetaminophen and vitamin D can be taken together. Patients with osteoarthritis who are on vitamin D and calcium may need to take Paracetamol / Acetaminophen for the relief of any associated pain. No drug interactions or any adverse effects have been reported.
Q. Can I take clindamycin with Paracetamol / Acetaminophen?
Paracetamol / Acetaminophen and Clindamycin can be taken together. Clindamycin is an antibiotic and is used to treat bacterial infections. Paracetamol / Acetaminophen may be given along, for the relief of associated fever. No drug-drug interactions have been reported clinically. However, both are known to cause liver damage. Talk to your doctor if you need them for a long time.
Q. Does Paracetamol / Acetaminophen affect the liver?
Usage of Paracetamol / Acetaminophen for a longer duration and more than advised doses can cause liver damage ranging from abnormal liver tests to liver failure. If you are taking Paracetamol / Acetaminophen from a long time and have nausea, stomach pain, loss of appetite, dark colored urine, clay colored stools or jaundice, inform your doctor as these could be signs of an underlying liver damage.
Q. Can I take Paracetamol / Acetaminophen if I have hepatitis?
Paracetamol / Acetaminophen is considered to be the safest painkiller for people with hepatitis for mild to moderate pain and fever. Paracetamol / Acetaminophen is metabolized in the liver. so, consult your physician before taking Paracetamol / Acetaminophen if you have hepatitis as it can cause liver damage if taken in higher doses or for longer duration.
Q. What are the serious side effects of taking excess Paracetamol / Acetaminophen?
Potentially critical life-threatening liver damage is a serious side effect observed with an overdose of Paracetamol / Acetaminophen. Overdose can also create kidney injury, coma, and reduced platelet count. Initial signs of an overdose include nausea, vomiting, and general tiredness. Immediately consult a physician or reach an emergency in case of suspected overdose.
Expert Advice
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.It should be taken with food or milk to avoid getting an upset stomach.It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.Piroxicam can raise your risk of blood clots, heart attack, or a stroke.Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Good for pain relief and fever but not effective in joint pain due to poor anti-inflammatory action.Starts working within one hour. Wait for at least 4 hours before taking the next dose.Present in many over-the-counter (OTC) and prescription medicines. Avoid taking more than one paracetamol product at a time to prevent overdose. Doses >4 g/day (2 g in alcoholics) may cause liver, kidney or heart problems.Discontinue Paracetamol / Acetaminophen and inform your doctor immediately if rash occurs.For children, measure the doses of liquid Paracetamol / Acetaminophen using the measuring cup instead of a teaspoon to avoid under or over-dosage.Avoid excess alcohol intake (>3 glasses/day) when taking Paracetamol / Acetaminophen as it may cause liver damage.
Product Details
SKU: PC-906382
Product Description: Doloforce Plus Tablet is manufactured by Mankind Pharma Ltd
Packing: Strip
Condition: New
Sold by: Pulse Pharmacy India Pvt. Ltd.
Product Description: Doloforce Plus Tablet is manufactured by Mankind Pharma Ltd
Packing: Strip
Condition: New
Sold by: Pulse Pharmacy India Pvt. Ltd.
