Consume this medicine in the dosage and duration as per your doctors advise. While taking Pioglitazone, swallow it completely without crushing, breaking or chewing it. Pioglitazone is advised to be taken at a fixed time, but may be taken together with food (or) without food.
Consume this medicine in the dosage and duration as per your doctors advise. While taking Glimepiride, swallow it completely without crushing, breaking or chewing it. Glimepiride is to be taken with food.
Q. Is Pioglitazone a blood thinner?
No. Pioglitazone is an anti-diabetic medication. Blood thinners are the medicine that prevents the formation of a harmful blood clot. These include medicines like Aspirin, Heparin and Warfarin.
Q. Is Pioglitazone a diuretic?
No. Pioglitazone is not a diuretic. It is used in the treatment of Diabetes Mellitus. Diuretics are those medicine which increases urination.
Q. Can Pioglitazone used in Hepatitis B infection?
Some studies have shown that Pioglitazone may be helpful in preventing Hepatitis B Virus-associated Hepatocellular Cancer (Liver Cancer). However, these findings are still very preliminary and clear role has not been established.
Q. Can Pioglitazone used in Hepatitis C infection?
Pioglitazone has been shown to inhibit Liver Cancer (HCC) recurrence in overweight Hepatitis C Virus-infected diabetic patients. It also improved insulin resistance (a state where the body is resistant to the effects and functions of the insulin hormone) in them.
Q. Can Pioglitazone used along with Vitamin D?
Studies indicate that Vitamin-D combined with Pioglitazone may be more effective in improving Bone Mineral Density and Bone Metabolism than Vitamin-D or Pioglitazone alone in the treatment of Diabetes Mellitus patients with kidney dysfunction (Diabetic Nephropathy).
Q. Can Pioglitazone be used along with sitagliptin?
Combination therapy with Sitagliptin and Pioglitazone leads to a substantial and sustained improvement in glycemic (blood sugar) control compared to the treatment with Pioglitazone alone. This is useful for patients who cannot tolerate Metformin or Sulfonylureas.
Q. Is there any role of Pioglitazone in Alzheimer disease?
Recent evidence suggests that Pioglitazone may be beneficial in Alzheimer's disease (AD), decreasing the cognitive decline early in the disease process. However, larger studies are now in progress to establish the same.
Q. Can Pioglitazone and repaglinide combined in diabetes treatment?
For patients who previously failed oral antidiabetic therapy, the combination of Repaglinide and Pioglitazone have acceptable safety, with greater reductions of glycemic parameters (blood sugar levels) than using either agent alone.
Q. Does Pioglitazone cause urinary bladder tumour?
Large population studies indicate that Pioglitazone is associated with an increased risk of bladder cancer. The absence of an association of bladder cancer with the other drug of the same class, Rosiglitazone, suggests that the increased risk is drug specific and not a class effect.
Q. Can Pioglitazone be used along with glimepiride in diabetes?
Pioglitazone when added to Glimepiride in Patients with Diabetes Mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood pressure control related to a reduction in the insulin resistance.
Q. Is Pioglitazone a steroid?
No. Pioglitazone is not a steroid. It is an anti-diabetic medication which belongs to the class of thiazolidinediones.
Q. How to use Pioglitazone?
Pioglitazone is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Pioglitazone acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.
Q. How safe is Pioglitazone?
Pioglitazone cardiovascular safety profile compares favourably with that of Rosiglitazone. Pioglitazone has been found to be associated with bladder tumours but causality assessment has not been proved yet.
Q. How does Pioglitazone cause oedema?
Pioglitazone increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Pioglitazone causes increased sodium and water reabsorption from the kidney that contributes to the oedema.
Q. How does Pioglitazone cause bladder cancer?
The mechanism behind the link between Pioglitazone use and bladder cancer is still unknown. Studies have suggested that use of Pioglitazone for more than one year results in increased risk of development of tumour of the urinary bladder.
Q. How Pioglitazone protects against atherosclerosis?
Studies in animals have concluded that Pioglitazone improves the elasticity of the aortic wall ( the aorta is a large blood vessel that arises from the heart and supplies oxygenated blood to the rest of the body). This may be a mechanism by which it protects against atherosclerosis, but more studies are needed to confirm this.
Q. Can Pioglitazone be used with insulin?
The addition of Pioglitazone reduces daily insulin dosages, but study findings have not been consistent. Improvement of lipid profiles has also been weak with this combination therapy. Long-term studies are needed before any conclusions can be reached. Combination therapy should be primarily used for patients who achieve an insufficient reduction in blood sugar with insulin alone.
Q. Can Pioglitazone used for dementia?
Findings indicate that Pioglitazone treatment is associated with a reduced dementia risk in Diabetes mellitus patients. Prospective studies are needed to evaluate a possible neuroprotective effect in these patients in an ageing population.
Q. Can Pioglitazone used for infertility?
Pioglitazone may be of use in infertile patients with polycystic ovary syndrome (PCOS) who are resistant to conventional ovulation induction such as by drugs like Clomiphene, Dexamethasone, or Metformin.
Q. Can Pioglitazone used for psoriasis?
The use of Pioglitazone for plaque psoriasis treatment is controversial. Some studies revealed no effect of Pioglitazone 30 mg daily neither on the clinical response of moderate-to-severe psoriasis whereas others demonstrate that it could be considered as an efficacious and safe agent for the treatment of plaque psoriasis.
Q. Can Pioglitazone used for autism?
In a research study in a small number of autistic children, daily treatment with 30 or 60 mg Pioglitazone for 3â€“4 months induced apparent clinical improvement. Pioglitazone should be considered for further testing of therapeutic potential in autistic patients but as of now, autism is not an approved indication for Pioglitazone use.
Q. Can Pioglitazone be used in depression?
Pioglitazone, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study.
Q. Can Pioglitazone used for weight loss?
A recent study shows that although Pioglitazone causes a significant decrease in blood sugar, HbA1C and lipid levels, it is associated with weight gain, which would limit its utility. It has not been shown to cause weight loss.
Q. Can Pioglitazone be used to treat fatty liver?
Pioglitazone has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.
Q. Can Pioglitazone be used for secondary stroke prevention?
Pioglitazone reduces recurrent stroke and major vascular events in stroke patients with insulin resistance, prediabetes, and diabetes mellitus. However, its use as a preventive therapy requires more research.
Q. Does Glimepiride play any role in the treatment of Polycystic ovarian syndrome (PCOS)?
No, Glimepiride is not known to have any part in the treatment of polycystic ovarian syndrome (PCOS).
Q. Is it safe to take Glimepiride and Sitagliptin together?
Intake of Glimepiride along with Sitagliptin can help in better control of blood sugar levels. But, the risk of low blood sugar levels (hypoglycemia) can increase. Hence Discuss your doctor as a dose adjustment of the two may be needed.
Q. Is Glimepiride useful in the management for prediabetes?
No, Glimepiride is not used for the control of Prediabetes, a condition with blood glucose levels higher than usual but not high enough to label you as diabetic.
Q. How is Glimepiride different from teneligliptin?
Both Glimepiride and teneligliptin work in different ways and have a different mechanism of action and side effects.
teneligliptin causes a headache and nasopharyngitis while Glimepiride generally causes hypoglycemia and weight gain. Teneligliptin used along with insulins or sulfonylureas may cause hypoglycemia and
does not cause weight gain. However, Glimepiride and teneligliptin are commonly antidiabetic medicines and both control blood sugar levels effectively.
Q. Can Glimepiride be given to elderly patients?
Yes, Glimepiride can be given to elderly patients. But they are more prone to the risk of low blood sugar levels (hypoglycemia), so important to monitor the blood sugar levels
regularly. Patients should be careful of the signs of hypoglycemia and always keep a quick source of sugar with them like a candy or a fruit juice.
Q. Can Glimepiride cause pancreatitis?
No, Glimepiride has not been reported to cause pancreatitis. But it may cause common side effects of low blood sugar level(hypoglycemia), headache, and dizziness, nausea.
Q. Can I skip Glimepiride for few days?
Skipping the drug Glimepiride is not advisable since it may cause diabetes even worse.
Q. Is it safe to take Glimepiride with pioglitazone?
Yes, Use of Glimepiride with Pioglitazone is safe in patients with diabetes mellitus. Both can help in better control of blood sugar levels. lower plasma lipid levels and increase blood pressure. But, the risk of low blood sugar levels (hypoglycemia) can increase. Hence Discuss your doctor as a dose adjustment of the two may be needed.
Q. Can I take Glimepiride if I have a sulfa allergy?
If you are allergic to sulfonylureas or sulfonamides or any of the other constituents of a drug Use of Glimepiride should be avoided.
Q. Does Glimepiride cause hair loss?
No, Glimepiride is not seen to cause hair loss. But diabetes itself can lead to hair loss. So Consult your doctor if you have undergone hair loss and it could be a symptom of your diabetes getting worsened
Q. Is it safe to take Glimepiride with vildagliptin?
Yes, Intake of Glimepiride along with Vildagliptin can help in better control of blood sugar levels. But, the risk of low blood sugar levels (hypoglycemia) can increase. Hence Discuss your doctor as a dose adjustment of the two may be needed.
Q. How is Glimepiride different from metformin?
Glimepiride and metformin are antidiabetic medicines and both control blood sugar levels effectively. but, Both work in different ways and have a different side effect. Glimepiride causes very low blood sugar levels and weight gain while Metformin causes more of stomach upset, like nausea, diarrhea and bloating, vomiting.
Q. How beneficial is it to take metformin with Glimepiride ?
Glimepiride and metformin are anti-diabetic medicines both are used to control blood sugar levels in a better way compared to either drug taken alone. But, Glimepiride can cause very low blood glucose levels, Hence necessary for monitoring of blood glucose level.
Q. Is Glimepiride useful in the management of gestational diabetes?
Glimepiride is not recommended for the management of gestational diabetes and insulin can be used to control the blood glucose levels at the time of pregnancy.
Q. Does Glimepiride cause weight gain?
While using Glimepiride it is advised to monitor
your diet and do regularly exercise as it may cause weight gain.
Do not skip your meal as it may very low blood sugar levels
and you may end up taking a lot of sugars.
Q. Is there any benefit of taking Glimepiride with insulin?
Glimepiride can be used with insulin to control high blood sugar, when taken together it may help to lower the dose of insulin but also increase the risk of hypoglycemia. so, adjustment of dose for these medications are required along with regular blood sugar level monitoring.
Q. Is it safe to take Glimepiride with liraglutide?
Intake of Glimepiride along with liraglutide can help in better control of blood sugar levels. But, the risk of low blood sugar levels (hypoglycemia) can increase. Hence Discuss your doctor as a dose adjustment of the two may be needed.
Q. Is Glimepiride a Thiazolidinedione?
Glimepiride and Thiazolidinedione are antidiabetic drugs. but comes under a different group of medicines. Hence Glimepiride is a sulfonylurea, it is not a Thiazolidinedione